Post-Doctoral Fellow - Dept. of Pharmacology and Toxicology

Virginia Commonwealth University is an equal opportunity, affirmative action university providing access to education and employment without regard to race, color, religion, national origin, age, sex, political affiliation, veteran status, genetic information, sexual orientation, gender identity, gender expression, or disability.

Position Summary:

There is an immediate opening for a joint Post Doctoral Fellow in the laboratories of Drs. E. Skordalakes and M. Hartman at Massy Cancer Center, VCU. The two laboratories are interested in developing cancer therapeutics that target KRAS, telomerase, and related complexes. In order to identify and validate the inhibitory activity of these molecules against KRAS and telomerase, we utilize a multidisciplinary approach involving hit discovery using mRNA display, followed by biochemical, biophysical, cell-based and animal studies for validation. Using structure-based drug design, we aim to elucidate the mechanism by which these molecules bind to their target proteins in order to improve their potency, therapeutic index, and physicochemical properties.

We are looking for highly motivated candidates that have recently acquired or will be acquiring a Ph.D. in structural biology and have a record of peer reviewed publications. The candidate must have a demonstrated commitment to fostering diversity and inclusion in past experiences or a commitment to do so as a Post-Doctoral Fellow at VCU.

Additional information regarding our research program can be found at the laboratories' web sites
https://pharmtox.vcu.edu/about/our-team/emmanuel-skordalakes-phd.html
https://chemistry.vcu.edu/directory/matthew-hartman.html

Interested applicants should e-mail their CV along with a cover letter briefly describing their research accomplishments and current research interests to Associate Professor, Emmanuel Skordalakes, Ph.D., (skordalakese@vcu.edu) and Professor, Matthew Hartman, Ph.D. (mchartman@vcu.edu).

The School of Medicine continuously strives for our workplace and learning environment to reflect the demographic and social milieu of the communities we serve. All qualified applicants are encouraged to apply.


This is a restricted position with no set end date and continued employment is dependent upon project need, availability of funding, and performance.


ORP Eligible: Yes

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